Il21 (NM_021782) Mouse Recombinant Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | Tag Free |
| Predicted MW | 14.2 kDa |
| Concentration | lot specific |
| Purity | >98%, as determined by Coomassie stained SDS-PAGE. |
| Buffer | 1 x PBS |
| Bioactivity | The ED50 is 15 - 60 ng/ml, corresponding to a specific activity of 1.7 - 6.7 x 10^4 units/mg. |
| Endotoxin | Less than 0.01 ng per µg protein as determined by the LAL method |
| Storage | Store at -80°C. |
| Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_068554 |
| Locus ID | 60505 |
| UniProt ID | Q9ES17 |
| Cytogenetics | 3 B |
| RefSeq Size | 3090 |
| RefSeq ORF | 438 |
| Synonyms | IL-21 |
| Summary | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.UniProtKB/Swiss-Prot Function |
| Protein Categories | Cytokines, Diabetes, Immune system diseases, Secreated Proteins |
Reviews
Documents
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Resources
| Recombinant Protein Resources |
Other "Il21" proteins (1)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TP526593 | Purified recombinant protein of Mouse interleukin 21 (Il21), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug | 20 ug |
$1,020.00
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Citations
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