Cxcl5 (NM_009141) Mouse Recombinant Protein

CAT#: TP723724

Purified recombinant protein of Mouse chemokine (C-X-C motif) ligand 5 (Cxcl5 / Lix)

Specifications

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse CXCL5, the region of Val45-Ala118, from gene Accession# NM_009141.2
• Tag: Tag Free
• Predicted MW: 8.0 kDa
• Concentration: lot specific
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: Recombinant mouse CXCL5 (LIX) chemoattracts Baf3-mCXCR2 transfectants in a dose-dependent manner. The ED50 for this effect is 0.06 – 0.36 ng/mL.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_033167
• Locus ID: 20311
• UniProt ID: P50228
• Cytogenetics: 5 44.78 cM
• Refseq Size: 1655
• Refseq ORF: 396
• Synonyms: AMCF; AMCF-II; Cxcl; Cxcl6; ENA-; ENA-78; GCP-; GCP-2; L; LIX; Scyb; Scyb5; Scyb6
• Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils and to have homeostatic and inflammatory functions. In mouse, deficiency of this gene is associated with increased lung inflammation that is neutrophil-dependent. [provided by RefSeq, May 2013]