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SECTM1 Human Recombinant Protein

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SKU
TP721363
APC Conjugated Human SECTM1 Protein (C-His)
Size:
25 ug 100 ug
  $430.00
5 Days*
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Frequently Bought Together (1)

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Other products for "SECTM1 or Q8WVN6"

Specifications
Specifications
Product Data
Species Human
Expression Host CHO
Expression cDNA Clone or AA Sequence
Protein Sequence
Gln29-Gly145
Tag C-His
Predicted MW The protein has a predicted molecular weight of 14kDa and migrates at approximately 20kDa on SDS-PAGE with DTT-reduced condition before APC conjugation.
Concentration 25µg size is bottled at 0.1mg/mL concentration. 100 µg size is bottled at lot specific concentration.
Purity >90%
Conjugation APC
Presentation State Purified
Buffer 1xPBS buffer, pH7.4, 0.09% NaN3 with a carrier protein
Bioactivity Positive

The definition of the active protein (purified and biotinylated) is defined as the protein that can bind to its biological receptor/ligand. For conjugated protein, it is defined with its function to bind to the ScFv of the active CAR-transfected cells in flow cytometry test.
Preparation Affinity Ni-NTA
Recommended Dilution FACS
Storage An unopened vial can be stored at 4°C for 2 weeks or at -20°C and below for six months. This stock solution should be aliquoted and stored at ≤ -70°C to minimize the freeze/thaw cycles.
Stability 6 Months
Shipping Blue Ice
Reference Data
RefSeq Q8WVN6
Locus ID 6398
UniProt ID Q8WVN6
Summary Human SECTM1 (secreted and transmembrance 1) is a type I transmembrane glycoprotein consisted of a 28 aa signal sequence, a 117 aa extracellular domain (ECD) with one potential N‑linked glycosylation site, a 21 aa transmembrane sequence, and an 82 aa cytoplasmic sequence. It is localized in the Golgi apparatus and exists as a transmembrane and a soluble form. SECTM1 protein expression is detected in some myeloid cells, such as stimulated monocytes, immature monocyte‑derived dendritic cells, and granulocytes. In the thymus, it is also expressed by epithelia and fibroblasts. Its expression is stimulated by IFN-gamma. Although its function is not well understood, the soluble N-terminus form of human SECTM1 demonstrates that it is a costimulatory ligand for human CD4 and CD8 T cell proliferation and cytokine production in CD7-dependent manner.
Protein Families FACS
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Other "SECTM1" proteins (6)
SKU Description Size Price
LC418959 Lyophilized SECTM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418959 Transient overexpression lysate of secreted and transmembrane 1 (SECTM1) (as WB positive control) 100 ug
$436.00
TP721359 Human SECTM1 Protein (C-His) 25 ug
$300.00
TP721360 Human SECTM1 Protein (C-His-Avi) 25 ug
$300.00
TP721361 Biotinylated Human SECTM1 Protein (C-His-Avi) 25 ug
$430.00
TP721362 PE Conjugated Human SECTM1 Protein (C-His) 25 ug
$430.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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