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Haptoglobin (HP) (NM_005143) Human Recombinant Protein

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SKU
TP721202
Purified recombinant protein of Human haptoglobin (HP), transcript variant 1
Size:
10 ug 500 ug 50 ug 1 mg
  $340.00
7 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Cys145-Asn406
Tag N-His
Predicted MW 31.4 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM EDTA, 5% Thehalose, pH 8.5.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_005134
Locus ID 3240
UniProt ID P00738
Cytogenetics 16q22.2
RefSeq Size 1433
RefSeq ORF 1218
Synonyms BP; HP2ALPHA2; HPA1S
Summary This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2014
Protein Categories Enzyme: Peptidases, Secreated Proteins
Protein Families Druggable Genome, Protease, Secreted Protein, Transmembrane
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Other "Haptoglobin" proteins (7)
SKU Description Size Price
PH323612 HP MS Standard C13 and N15-labeled recombinant protein (NP_005134) 10 ug
$3,360.00
LC401576 Lyophilized HP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426644 Lyophilized HP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401576 Transient overexpression lysate of haptoglobin (HP), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY426644 Transient overexpression lysate of haptoglobin (HP), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP323612 Recombinant protein of human haptoglobin (HP), transcript variant 1, 20 µg 20 ug
$737.00
TP721131 Purified recombinant protein of Human haptoglobin (HP), transcript variant 1 10 ug
$340.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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