Haptoglobin (HP) (NM_005143) Human Recombinant Protein
$737.00
5 Days*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 43.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005134 |
| Locus ID | 3240 |
| UniProt ID | P00738 |
| Cytogenetics | 16q22.2 |
| RefSeq Size | 1433 |
| RefSeq ORF | 1218 |
| Synonyms | BP; HP2ALPHA2; HPA1S |
| Summary | This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2014 |
| Protein Categories | Enzyme: Peptidases, Secreated Proteins |
| Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Haptoglobin" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH323612 | HP MS Standard C13 and N15-labeled recombinant protein (NP_005134) | 10 ug |
$3,360.00
|
|
| LC401576 | Lyophilized HP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426644 | Lyophilized HP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401576 | Transient overexpression lysate of haptoglobin (HP), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426644 | Transient overexpression lysate of haptoglobin (HP), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP721131 | Purified recombinant protein of Human haptoglobin (HP), transcript variant 1 | 10 ug |
$340.00
|
|
| TP721202 | Purified recombinant protein of Human haptoglobin (HP), transcript variant 1 | 10 ug |
$340.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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