Junctional Adhesion Molecule 2 (JAM2) (NM_021219) Human Recombinant Protein
Purified recombinant protein of Human junctional adhesion molecule 2 (JAM2)
Product Datasheet for 'TP721088'
|Description||Purified recombinant protein of Human junctional adhesion molecule 2 (JAM2)|
|Expression cDNA Clone or AA Sequence||FSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK|
|Predicted MW||50.3 kDa|
|Concentration||Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.|
|Purity||>95% as determined by SDS-PAGE and Coomassie blue staining|
|Buffer||Lyophilized from a 0.2 µM filtered solution of PBS,pH 7.4|
|Endotoxin||Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).|
|Synonyms||C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM|
|Summary||This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]|
|Protein Families||Druggable Genome, Transmembrane|
|Protein Pathways||Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction|
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