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STAT5B (NM_012448) Human Recombinant Protein

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SKU
TP720975
Purified recombinant protein of Human signal transducer and activator of transcription 5B (STAT5B)
Size:
10 ug 500 ug 50 ug 1 mg
  $340.00
7 Weeks*
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Frequently Bought Together (1)

TA382101 STAT5B Rabbit polyclonal Antibody
100 ul
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Met1-Thr321
Tag C-His
Predicted MW 38.4 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of PBS, 50% Glycerol, 1mM DTT, pH 7.4.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_036580
Locus ID 6777
UniProt ID P51692
Cytogenetics 17q21.2
RefSeq Size 5171
RefSeq ORF 2361
Synonyms GHISID2; STAT5
Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Growth Factors, Immune system diseases, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Acute myeloid leukemia, Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Jak-STAT signaling pathway, Pathways in cancer
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Other "STAT5B" proteins (4)
SKU Description Size Price
PH309429 STAT5B MS Standard C13 and N15-labeled recombinant protein (NP_036580) 10 ug
$3,360.00
LC415754 Lyophilized STAT5B HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415754 Transient overexpression lysate of signal transducer and activator of transcription 5B (STAT5B) (as WB positive control) 100 ug
$436.00
TP309429 Recombinant protein of human signal transducer and activator of transcription 5B (STAT5B), 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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