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BIRC5 (NM_001168) Human Recombinant Protein

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SKU
TP720853
Purified recombinant protein of Human baculoviral IAP repeat containing 5 (BIRC5/Survivin), transcript variant 1
Size:
10 ug 500 ug 50 ug 1 mg
  $260.00
15 Weeks*
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Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Met1-Asp142
Tag Tag Free
Predicted MW 16.3 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM Tris, 0.3M NaCl, 2mM EDTA, pH 8.0
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_001159
Locus ID 332
UniProt ID O15392
Cytogenetics 17q25.3
Synonyms API4; EPR-1
Summary This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jun 2011
Protein Categories Cytokines, Intracellular Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Colorectal cancer, Pathways in cancer
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Documents
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Other "BIRC5" proteins (9)
SKU Description Size Price
PH305935 BIRC5/Survivin MS Standard C13 and N15-labeled recombinant protein (NP_001159) 10 ug
$3,360.00
LC400469 Lyophilized BIRC5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423314 Lyophilized BIRC5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423315 Lyophilized BIRC5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400469 Transient overexpression lysate of baculoviral IAP repeat-containing 5 (BIRC5/Survivin), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY423314 Transient overexpression lysate of baculoviral IAP repeat-containing 5 (BIRC5/Survivin), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY423315 Transient overexpression lysate of baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP305935 Recombinant protein of human baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 1, 20 µg 20 ug
$737.00
TP750221 Purified recombinant protein of Human baculoviral IAP repeat containing 5 (BIRC5/Survivin), transcript variant 2, full length, with C-terminal DDK tag, expressed in E.coli, 50ug 50 ug
$240.00

file-alt Citations

CCN1 induces apoptosis in esophageal adenocarcinoma through p53-dependent downregulation of survivin
Dang, Modak, Meng et al
J Cell Biochem (2019) 120 (2), 2070-2077 DOI: 10.1002/jcb.27515
Cited by 14
AI Summary: In this study, OriGene products including the p53 shRNA plasmid (OriGene, Cat# TL312815) and survivin antibody (OriGene, Cat# TA800927) were used to investigate the roles of p53 and survivin in CCN1-induced apoptosis in esophageal adenocarcinoma cells.
Showing 1-1 of 1 papers.
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