SGSH (NM_000199) Human Recombinant Protein

CAT#: TP720741

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Purified recombinant protein of Human N-sulfoglucosamine sulfohydrolase (SGSH)


 Product Datasheet for 'TP720741'

  View other "SGSH" proteins (4)

USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human N-sulfoglucosamine sulfohydrolase (SGSH)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNELVDHHHHHH
Tag C-His
Predicted MW 55.72 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 µM filtered solution of '20mM TrisHCl,150mM NaCl,1mM GaCl2,10%Glycerol,pH7.5
Endotoxin Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Reference Data
RefSeq NP_000190
Locus ID 6448
Refseq Size 2770
Cytogenetics 17q25.3
Refseq ORF 1506
Synonyms HSS; MPS3A; SFMD
Summary This gene encodes the enzyme sulfamidase; one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq, Jun 2017]
Protein Families Druggable Genome
Protein Pathways Glycosaminoglycan degradation, Lysosome, Metabolic pathways

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Rabbit polyclonal antibody to SGSH (N-sulfoglucosamine sulfohydrolase)
    • 100 ul

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BOGO Free lysates
68 Mouse Clones
HUMAN PROREINS 101