CER1 (NM_005454) Human Recombinant Protein

CAT#: TP720692

Purified recombinant protein of Human cerberus 1, DAN family BMP antagonist (CER1)

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Thr18-Ala267
• Tag: C-His
• Predicted MW: 29.19 kDa
• Concentration: N/A
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in 20mM NaAc-HAC. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_005445
• Locus ID: 9350
• UniProt ID: O95813
• Cytogenetics: 9p22.3
• Refseq Size: 1206
• Refseq ORF: 801
• Synonyms: DAND4
• Summary: This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]
• Protein Families: Secreted Protein
• Protein Pathways: Wnt signaling pathway