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CD73 (NT5E) (NM_002526) Human Recombinant Protein

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SKU
TP720666
Purified recombinant protein of Human 5'-nucleotidase, ecto (CD73) (NT5E), transcript variant 1
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  $340.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Trp27-Lys547
Tag C-His
Predicted MW 58.76 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 120mM NaCl, 4mM CaCl2, 20% Glycerol, pH 7.5.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_002517
Locus ID 4907
UniProt ID P21589
Cytogenetics 6q14.3
RefSeq Size 4086
RefSeq ORF 1722
Synonyms CALJA; CD73; E5NT; eN; eNT; NT; NT5; NTE
Summary The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Mar 2011
Protein Categories ADC Targets, Cardiovascular diseases, CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Metabolic pathways, Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism
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Other "CD73" proteins (2)
SKU Description Size Price
LC419270 Lyophilized NT5E HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419270 Transient overexpression lysate of 5'-nucleotidase, ecto (CD73) (NT5E) (as WB positive control) 100 ug
$436.00

file-alt Citations

Virtual Screening Approach for the Identification of Hydroxamic Acids as Novel Human Ecto-5'-Nucleotidase Inhibitors
Viviani, Piccirillo, Ulrich et al
J Chem Inf Model (2019)
AI Summary: OriGene’s purified recombinant human ecto-5'-nucleotidase was used in this study to experimentally evaluate the inhibitory activity of candidate compounds identified through virtual screening.
Snippet: Purified recombinant human ecto-5'-nucleotidase was commercially obtained from OriGene Technologies, Inc.;adenosine monophosphate (≥ 99%), calcium chloride dihydrate (≥ 99%), and dimethyl sulfoxide (DMSO) were obtained from Sigma Aldrich, Inc.;CHAPS
Showing 1-1 of 1 papers.
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