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Galectin 3 (LGALS3) (NM_002306) Human Recombinant Protein

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SKU
TP720583
Purified recombinant protein of Human lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1
Size:
10 ug 500 ug 50 ug 1 mg
  $190.00
7 Weeks*
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Frequently Bought Together (1)

TA801621BM LGALS3 mouse monoclonal antibody, clone OTI1C7 (formerly 1C7), HRP conjugated 100 ul
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Ala2-Ile250
Tag Tag Free
Predicted MW 26 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 50mMHEPES,150mMNacl,5% Trehalose,pH7.4.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_002297
Locus ID 3958
UniProt ID P17931
Cytogenetics 14q22.3
RefSeq Size 1017
RefSeq ORF 750
Synonyms CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
Summary This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.provided by RefSeq, Oct 2014
Protein Categories Intracellular Proteins, Secreated Proteins
Protein Families Secreted Protein
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Other "Galectin 3" proteins (4)
SKU Description Size Price
PH308785 LGALS3 MS Standard C13 and N15-labeled recombinant protein (NP_002297) 10 ug
$3,360.00
LC400834 Lyophilized LGALS3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400834 Transient overexpression lysate of lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP308785 Recombinant protein of human lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1, 20 µg 20 ug
$867.00

file-alt Citations

Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies
Stasenko, Smith, Yeku et al
Sci Rep (2021) 11 (1), 3718 DOI: 10.1038/s41598-021-82686-3
Cited by 34
AI Summary: OriGene’s human LGALS3 protein was used as an immunogen to generate and screen antibodies against galectin-3, enabling the development of the inhibitory anti-Gal3 antibody 14D11 described in the study.
Snippet: …The last 2 immunizations used human LGALS3 protein (OriGene;Rockville, MD). The immune sera from the mice were collected at the time of every immunization and screened for reactivity against LGALS3 by ELISA
FigureFigureFigure
Showing 1-1 of 1 papers.
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