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CD8B (NM_001178100) Human Recombinant Protein

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SKU
TP720467
Recombinant protein of human CD8b molecule (CD8B), transcript variant 6.
Size:
10 ug 500 ug 50 ug 1 mg
  $275.00
5 Days*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Leu22-Pro170
Tag C-His
Predicted MW 17.8 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_001171571
Locus ID 926
UniProt ID P10966
Cytogenetics 2p11.2
Synonyms CD8B1; LEU2; LY3; LYT3; P37
Summary The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. provided by RefSeq, May 2010
Protein Categories CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
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Other "CD8B" proteins (4)
SKU Description Size Price
LC406743 Lyophilized CD8B HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC432674 Lyophilized CD8B HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY406743 Transient overexpression lysate of CD8b molecule (CD8B), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY432674 Transient overexpression lysate of CD8b molecule (CD8B), transcript variant 6 (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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