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LIMPII (SCARB2) (NM_005506) Human Recombinant Protein

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SKU
TP720440
Recombinant protein of human scavenger receptor class B, member 2 (SCARB2)
Size:
10 ug 500 ug 50 ug 1 mg
  $310.00
5 Days*
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Arg27-Thr432
Tag C-His
Predicted MW 47.6 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reconstitution Method Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in ddH2O. It is not recommended to reconstitute a concentration less than 100 µg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Shipping Ambient
Reference Data
RefSeq NP_005497
Locus ID 950
UniProt ID Q14108
Cytogenetics 4q21.1
Synonyms AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII
Summary The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Feb 2011
Protein Categories Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Transmembrane
Protein Pathways Lysosome
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Other "LIMPII" proteins (4)
SKU Description Size Price
PH302162 SCARB2 MS Standard C13 and N15-labeled recombinant protein (NP_005497) 10 ug
$3,360.00
LC401685 Lyophilized SCARB2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401685 Transient overexpression lysate of scavenger receptor class B, member 2 (SCARB2) (as WB positive control) 100 ug
$436.00
TP302162 Recombinant protein of human scavenger receptor class B, member 2 (SCARB2), 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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