B4GALT4 (NM_003778) Human Recombinant Protein

CAT#: TP720426

Recombinant protein of human UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 (B4GALT4), transcript variant 2


 Product Datasheet for 'TP720426'

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USD 299.00


Availability*
5 Days

Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 (B4GALT4), transcript variant 2
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC209493, encoding the secreted form (Gln39-Ala344) of human B4GALT4
Tag N-GST and HIS
Predicted MW 36.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer 20mM Tris, 150mM NaCl, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_003769
Locus ID 8702
Refseq Size 2283
Cytogenetics 3q13.32
Refseq ORF 1035
Synonyms B4Gal-T4; beta4Gal-T4
Summary This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Transmembrane
Protein Pathways Keratan sulfate biosynthesis, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways

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B4GALT4 mouse monoclonal antibody, clone OTI8B6 (formerly 8B6)
    • 100 ul

USD 360.00

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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