CTRB1 (NM_001906) Human Recombinant Protein

SKU
TP720408
Recombinant Human Chymotrypsingen B/CTRB
  $275.00
7 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Cys19-Asn263
Tag C-His
Predicted MW 26.9 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001897
Locus ID 1504
UniProt ID P17538
Cytogenetics 16q23.1
Synonyms CTRB
Summary This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This CTRB1 gene is located head-to-head with the related CTRB2 gene. Some human populations have an alternate haplotype which inverts a 16.6 Kb region containing portions of intron 1, exon 1, and the upstream sequence of the CTRB1 and CTRB2 genes. In this inversion haplotype exon 1 and flanking sequence is swapped in CTRB1 and CTRB2. This inversion is associated with differential gene expression and increased risk for chronic pancreatitis. The GRCh38 assembly represents the minor allele for SNP rs8048956 of the CTRB1 gene. SNP rs8048956 in intron 1 of the CTRB2 gene is diagnostic for this inversion. This CTRB1 gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. provided by RefSeq, Jan 2021
Protein Categories Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Protease, Secreted Protein, Transmembrane
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Other "CTRB1" proteins (4)
SKU Description Size Price
PH302806 CTRB1 MS Standard C13 and N15-labeled recombinant protein (NP_001897) 10 ug
$3,360.00
LC419664 Lyophilized CTRB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419664 Transient overexpression lysate of chymotrypsinogen B1 (CTRB1) (as WB positive control) 100 ug
$436.00
TP302806 Recombinant protein of human chymotrypsinogen B1 (CTRB1), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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