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Cathepsin B (CTSB) (NM_001908) Human Recombinant Protein

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SKU
TP720340
Recombinant protein of human cathepsin B (CTSB), transcript variant 1
Size:
10 ug 500 ug 50 ug 1 mg
  $340.00
7 Weeks*
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Other products for "Cathepsin B or NM_001908"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
Tag C-6xHis
Predicted MW 36.9 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of PBS, pH 7.4.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001899
Locus ID 1508
UniProt ID P07858
Cytogenetics 8p23.1
Synonyms APPS; CPSB; RECEUP
Summary This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell. Multiple pseudogenes of this gene have been identified. provided by RefSeq, Sep 2020
Protein Categories Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, Protease
Protein Pathways Antigen processing and presentation, Lysosome
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Other "Cathepsin B" proteins (20)
SKU Description Size Price
PH310578 CTSB MS Standard C13 and N15-labeled recombinant protein (NP_680093) 10 ug
$3,360.00
PH322289 CTSB MS Standard C13 and N15-labeled recombinant protein (NP_001899) 10 ug
$3,360.00
PH322463 CTSB MS Standard C13 and N15-labeled recombinant protein (NP_680092) 10 ug
$3,360.00
PH322764 CTSB MS Standard C13 and N15-labeled recombinant protein (NP_680091) 10 ug
$3,360.00
LC403447 Lyophilized CTSB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC407800 Lyophilized CTSB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC407801 Lyophilized CTSB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC407802 Lyophilized CTSB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419666 Lyophilized CTSB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC430182 Lyophilized CTSB HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403447 Transient overexpression lysate of cathepsin B (CTSB), transcript variant 5 (as WB positive control) 100 ug
$436.00
LY407800 Transient overexpression lysate of cathepsin B (CTSB), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY407801 Transient overexpression lysate of cathepsin B (CTSB), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY407802 Transient overexpression lysate of cathepsin B (CTSB), transcript variant 4 (as WB positive control) 100 ug
$436.00
LY419666 Transient overexpression lysate of cathepsin B (CTSB), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY430182 Transient overexpression lysate of cathepsin B (CTSB), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP310578 Recombinant protein of human cathepsin B (CTSB), transcript variant 5, 20 µg 20 ug
$867.00
TP322289 Recombinant protein of human cathepsin B (CTSB), transcript variant 1, 20 µg 20 ug
$867.00
TP322463 Purified recombinant protein of Homo sapiens cathepsin B (CTSB), transcript variant 4, 20 µg 20 ug
$867.00
TP322764 Purified recombinant protein of Homo sapiens cathepsin B (CTSB), transcript variant 3, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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