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FH (NM_000143) Human Recombinant Protein

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SKU
TP720199
Recombinant protein of human fumarate hydratase (FH), nuclear gene encoding mitochondrial protein
Size:
10 ug 500 ug 50 ug 1 mg
  $340.00
7 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Ala45-Lys510
Tag Tag Free
Predicted MW 50.2 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris, pH 8.0.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000134
Locus ID 2271
UniProt ID P07954
Cytogenetics 1q43
Synonyms FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1
Summary The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. provided by RefSeq, Jul 2008
Protein Categories Cancer: Bladder, Cancer: Endocrine, Endocrine and metabolic diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma
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Other "FH" proteins (4)
SKU Description Size Price
PH300614 FH MS Standard C13 and N15-labeled recombinant protein (NP_000134) 10 ug
$3,360.00
LC400053 Lyophilized FH HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400053 Transient overexpression lysate of fumarate hydratase (FH), nuclear gene encoding mitochondrial protein (as WB positive control) 100 ug
$436.00
TP300614 Recombinant protein of human fumarate hydratase (FH), nuclear gene encoding mitochondrial protein, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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