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Aldolase (ALDOA) (NM_000034) Human Recombinant Protein

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SKU
TP720179
Recombinant protein of human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1
Size:
10 ug 500 ug 50 ug 1 mg
  $275.00
7 Weeks*
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Frequently Bought Together (1)

TA321043 Anti-ALDOA rabbit polyclonal antibody
100 ul
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Other products for "Aldolase or NM_000034"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Pro2-Tyr364
Tag C-His
Predicted MW 40.5 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 100mM NaCl, 20% Glycerol, pH 8.0.
Bioactivity Enzyme activity regulator (PMID: 29084207)
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000025
Locus ID 226
UniProt ID P04075 V9HWN7
Cytogenetics 16p11.2
Synonyms ALDA; GSD12; HEL-S-87p
Summary This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. provided by RefSeq, Sep 2017
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway
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Other "Aldolase" proteins (16)
SKU Description Size Price
PH302576 ALDOA MS Standard C13 and N15-labeled recombinant protein (NP_000025) 10 ug
$3,360.00
PH303900 ALDOA MS Standard C13 and N15-labeled recombinant protein (NP_908930) 10 ug
$3,360.00
PH303908 ALDOA MS Standard C13 and N15-labeled recombinant protein (NP_908932) 10 ug
$3,360.00
PH325547 ALDOA MS Standard C13 and N15-labeled recombinant protein (NP_001121089) 10 ug
$3,360.00
LC400006 Lyophilized ALDOA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405206 Lyophilized ALDOA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC405207 Lyophilized ALDOA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426825 Lyophilized ALDOA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400006 Transient overexpression lysate of aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY405206 Transient overexpression lysate of aldolase A, fructose-bisphosphate (ALDOA), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY405207 Transient overexpression lysate of aldolase A, fructose-bisphosphate (ALDOA), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY426825 Transient overexpression lysate of aldolase A, fructose-bisphosphate (ALDOA), transcript variant 4 (as WB positive control) 100 ug
$436.00
TP302576 Recombinant protein of human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 1, 20 µg 20 ug
$737.00
TP303900 Recombinant protein of human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 2, 20 µg 20 ug
$737.00
TP303908 Recombinant protein of human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 3, 20 µg 20 ug
$737.00
TP325547 Recombinant protein of human aldolase A, fructose-bisphosphate (ALDOA), transcript variant 4, 20 µg 20 ug
$737.00

file-alt Citations

Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth
Ma, Chen, Zhang et al
Oncogene (2017)
Cited by 65
AI Summary: OriGene’s purified recombinant ALDOA protein was used to assess its effect on DNA-PK activity, helping to elucidate the role of ALDOA in the ALDOA/DNA-PK/p53 pathway underlying the antitumor effects of dietary restriction.
Snippet: The ADP-Glo Kinase Assay (Promega) and DNA-PK Kinase Enzyme System (Promega) were used to characterize the effect of purified recombinant protein ALDOA (OriGene, Rockville, MD, USA) on the activity of native DNA-PK (Promega), which was purified from HeLa
Showing 1-1 of 1 papers.
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