RANTES (CCL5) (NM_002985) Human Recombinant Protein
Specifications
Product Data | |
Description | Recombinant protein of human chemokine (C-C motif) ligand 5 (CCL5) |
Species | Human |
Expression Host | E. coli |
Tag | Tag Free |
Predicted MW | 7.8 kDa |
Concentration | Resuspend the protein to the desired concentration in proper buffer. |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.4. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_002976 |
Locus ID | 6352 |
Refseq Size | 1237 |
Cytogenetics | 17q12 |
Refseq ORF | 273 |
Synonyms | D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228 |
Summary | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway |
Documents
FAQs |
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Resources
Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TP723373 | Purified recombinant protein of Human chemokine (C-C motif) ligand 5 (CCL5). |
USD 230.00 |
|
LC401044 | CCL5 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 95.00 |
|
TP723778 | Purified recombinant protein of Human chemokine (C-C motif) ligand 5 (CCL5 / RANTES) |
USD 195.00 |
|
AR09257PU-N | Recombinant RANTES protein was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 570.00 |
|
AR09257PU-L | Recombinant RANTES protein was expressed in E.coli and purified by using conventional chromatography techniques. |
USD 1,570.00 |
|
TP303799 | Recombinant protein of human chemokine (C-C motif) ligand 5 (CCL5) |
USD 748.00 |
|
LY401044 | Transient overexpression lysate of chemokine (C-C motif) ligand 5 (CCL5) |
USD 315.00 |
|
PH303799 | CCL5 MS Standard C13 and N15-labeled recombinant protein (NP_002976) |
USD 1,995.00 |
|
LC830143 | CCL5-knockout Cell lysate from HeLa cell line, one vial of parental cell line lysate included as control |
USD 495.00 |
USD 425.00