TLE3 (NM_005078) Human Recombinant Protein

SKU TP710181

Recombinant protein of human transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) (TLE3), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9, 20ug

Product Data

• Species: Human
• Expression Host: Sf9
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, [RC224066], encoding human full-length TLE3
• Tag: C-DDK
• Predicted MW: 83.4 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_005069
• Locus ID: 7090
• UniProt ID: Q04726
• Cytogenetics: 15q23
• RefSeq Size: 5354
• RefSeq ORF: 2316
• Synonyms: ESG; ESG3; GRG3; HsT18976
• Summary: This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
• Protein Families: Transcription Factors