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TrkC (NTRK3) (NM_001012338) Human Recombinant Protein

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SKU
TP710140
Recombinant protein of human mitotic spindle organizing protein 2A (MZT2A), residues 32-429aa, with C-terminal DDK tag, expressed in sf9, 20ug
Size:
20 ug
  $540.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC219113, encoding the region(Cys32-Thr429) of Homo sapiens NTRK3
Tag C-DDK
Predicted MW 44.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001012338
Locus ID 4916
UniProt ID Q16288
Cytogenetics 15q25.3
RefSeq Size 2860
RefSeq ORF 2517
Synonyms gp145(trkC); GP145-TrkC; TRKC
Summary This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2011
Protein Categories Cancer: Brain and CNS, Cancer: Head and Neck, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Neurotrophin signaling pathway
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Other "TrkC" proteins (9)
SKU Description Size Price
PH303781 NTRK3 MS Standard C13 and N15-labeled recombinant protein (NP_001007157) 10 ug
$3,360.00
PH313333 NTRK3 MS Standard C13 and N15-labeled recombinant protein (NP_002521) 10 ug
$3,360.00
PH319113 NTRK3 MS Standard C13 and N15-labeled recombinant protein (NP_001012338) 10 ug
$3,360.00
LC400902 Lyophilized NTRK3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400902 Transient overexpression lysate of neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP303781 Recombinant protein of human neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 3, 20 µg 20 ug
$867.00
TP313333 Recombinant protein of human neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 2, 20 µg 20 ug
$867.00
TP319113 Recombinant protein of human neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 1, 20 µg 20 ug
$867.00
TP700136 Purified recombinant protein of human neurotrophic tyrosine kinase, receptor, type 3 (NTRK3), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg 20 ug
$900.00

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