DCK (NM_000788) Human Recombinant Protein

CAT#: TP710018

Recombinant protein of human deoxycytidine kinase (DCK), full length with N-terminal polyhistidine tag, expressed in sf9 cells.


  View other "DCK" proteins (6)

USD 515.00

In Stock*

Size
    • 20 ug

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Frequently bought together (1)
DCK mouse monoclonal antibody, clone OTI16G6 (formerly 16G6)
    • 100 ul

USD 447.00

Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC210767, encoding human full-length DCK
Tag N-His
Predicted MW 30 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 20% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000779
Locus ID 1633
UniProt ID P27707, F5CTF3
Cytogenetics 4q13.3
Refseq Size 2618
Refseq ORF 780
Summary Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Purine metabolism, Pyrimidine metabolism

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