Thymidine Kinase 1 (TK1) (NM_003258) Human Recombinant Protein

CAT#: TP700037

Reviews ()
Write a review

Recombinant protein of human thymidine kinase 1, soluble (TK1), expressed in human cells



  View other "TK1" proteins (2)

USD 748.00


Availability*
In Stock

Size
    • 20 ug


Product images

Specifications

Product Data
Description Recombinant protein of human thymidine kinase 1, soluble (TK1), expressed in human cells
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC218280, encoding human full-length TK1
Tag C-DDK
Predicted MW 27 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003249
Locus ID 7083
Refseq Size 1616
Cytogenetics 17q25.3
Refseq ORF 113
Synonyms TK2
Summary The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [provided by RefSeq, Oct 2016]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Documents

Other Versions

Frequently bought together (1)
Rabbit polyclonal TK (Ab-13) antibody
    • 100 ul

USD 345.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
Molbio tools
HUMAN PROREINS 101