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Il17ra (NM_008359) Mouse Recombinant Protein

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SKU
TP526704
Purified recombinant protein of Mouse interleukin 17 receptor A (Il17ra), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR226704 representing NM_008359
Red=Cloning site Green=Tags(s)

MAIRRCWPRVVPGPALGWLLLLLNVLAPGRASPRLLDFPAPVCAQEGLSCRVKNSTCLDDSWIHPKNLTP
SSPKNIYINLSVSSTQHGELVPVLHVEWTLQTDASILYLEGAELSVLQLNTNERLCVKFQFLSMLQHHRK
RWRFSFSHFVVDPGQEYEVTVHHLPKPIPDGDPNHKSKIIFVPDCEDSKMKMTTSCVSSGSLWDPNITVE
TLDTQHLRVDFTLWNESTPYQVLLESFSDSENHSCFDVVKQIFAPRQEEFHQRANVTFTLSKFHWCCHHH
VQVQPFFSSCLNDCLRHAVTVPCPVISNTTVPKPVADYIPLWVYGLITLIAILLVGSVIVLIICMTWRLS
GADQEKHGDDSKINGILPVADLTPPPLRPRKVWIVYSADHPLYVEVVLKFAQFLITACGTEVALDLLEEQ
VISEVGVMTWVSRQKQEMVESNSKIIILCSRGTQAKWKAILGWAEPAVQLRCDHWKPAGDLFTAAMNMIL
PDFKRPACFGTYVVCYFSGICSERDVPDLFNITSRYPLMDRFEEVYFRIQDLEMFEPGRMHHVRELTGDN
YLQSPSGRQLKEAVLRFQEWQTQCPDWFERENLCLADGQDLPSLDEEVFEDPLLPPGGGIVKQQPLVREL
PSDGCLVVDVCVSEEESRMAKLDPQLWPQRELVAHTLQSMVLPAEQVPAAHVVEPLHLPDGSGAAAQLPM
TEDSEACPLLGVQRNSILCLPVDSDDLPLCSTPMMSPDHLQGDAREQLESLMLSVLQQSLSGQPLESWPR
PEVVLEGCTPSEEEQRQSVQSDQGYISRSSPQPPEWLTEEEELELGEPVESLSPEELRSLRKLQRQLFFW
ELEKNPGWNSLEPRRPTPEEQNPS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 98.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_032385
Locus ID 16172
UniProt ID Q60943
Cytogenetics 6 56.95 cM
RefSeq Size 3970
RefSeq ORF 2592
Synonyms AW538159; Cdw217; Il17r; VDw217
Summary Receptor for IL17A (PubMed:17911633, PubMed:20554964, PubMed:8777726). Receptor for IL17F (PubMed:17911633, PubMed:20554964). Binds to IL17A with higher affinity than to IL17F (PubMed:17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (By similarity). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (By similarity). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848, PubMed:21993849, PubMed:21982598). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories CD Markers, Chemokines, Cytokines, Immune system diseases, Membrane Proteins, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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