Cdk6 (NM_009873) Mouse Recombinant Protein
SKU
TP525890
Purified recombinant protein of Mouse cyclin-dependent kinase 6 (Cdk6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
$1,020.00
4 Weeks*
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 37.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_034003 |
| Locus ID | 12571 |
| UniProt ID | Q64261 |
| Cytogenetics | 5 2.04 cM |
| RefSeq Size | 2470 |
| RefSeq ORF | 978 |
| Synonyms | AI504062; Crk; Crk2 |
| Summary | This gene encodes a member of the cyclin dependent kinase family of proteins that play important roles in the progression and regulation of the cell cycle. The encoded protein binds to a D-type cyclin to form an active kinase complex to regulate progression through the G1 phase of the cell cycle. Mice lacking the encoded protein exhibit thymic and splenic hypoplasia, and hematopoietic defects such as reduced number of megakaryocytes and erythrocytes. A pseudogene of this gene has been defined on chromosome 4. provided by RefSeq, Aug 2015 |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthinol
Iizumi, Sowa, Goi et al
Commun Biol (2022) 5 (1), 564 DOI: 10.1038/s42003-022-03522-6
Iizumi, Sowa, Goi et al
Commun Biol (2022) 5 (1), 564 DOI: 10.1038/s42003-022-03522-6
Cited by 6
AI Summary: OriGene’s DDK antibody (TA50011-100) was used for immunodetection in this study to analyze protein expression levels, contributing to the investigation of CDK6 stabilization mechanisms.
Snippet: or ab210745, Abcam, Cambridge, UK, 1:500 or 1:1000 dilution), uS9 (ab26159, Abcam, 1:500 dilution), uS4 (ab74711, Abcam, 1:1000 dilution), uL3 (ab241412, Abcam, 1:500 dilution), and DDK (TA50011-100, OriGene Technologies, Rockville, MD, USA, 1:500 dilution). The membranes were then incubated with HRP-linked anti-rabbit IgG (NA934V, GE Healthcare, Chicago, IL, USA, 1:2000 dilution) or HRP-linked an;, Cambridge, UK, 1:500 or 1:1000 dilution), uS9 (ab26159, Abcam, 1:500 dilution), uS4 (ab74711, Abcam, 1:1000 dilution), uL3 (ab241412, Abcam, 1:500 dilution), and DDK (TA50011-100, OriGene Technologies, Rockville, MD, USA, 1:500 dilution). …
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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