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Ankfy1 (NM_009671) Mouse Recombinant Protein

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SKU
TP524779
Purified recombinant protein of Mouse ankyrin repeat and FYVE domain containing 1 (Ankfy1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR224779 representing NM_009671
Red=Cloning site Green=Tags(s)

MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCTLLAAQANKENSNESFISRLLAIVAGLYEQEQYSDL
KIKVGDRHISAHKFVLAARSDSWSLANLSSTEEIDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMK
LANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSLSAQLL
YKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSHKA
DVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIA
EALLQAGANPNMQDSKGRTPLHLSIMARNDCVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSV
NPFEDLPVVNGTSFDENSFAARLIQRGSNTDAPDVMTGNCLLQRAAGAGNEAAALFLATSGAHANHRNKW
GETPLHTACRHGLANLTAELLQQGANPNLQTEEALPVPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVS
VILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAI
QRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMSVPDEKGNPPLWLALASNL
EDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDG
QTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPVHVAISNQHSVIIQLLISHPNIELSVRDRQGLTP
FACAMTYKNNKAAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPL
HLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAV
MHGRLNNIRALLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPEYPLDKPDAEGNTVLLL
AYMKGNANLCRAIVRSGVRLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVT
TRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 128.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_033801
Locus ID 11736
UniProt ID Q810B6
Cytogenetics 11 B4
RefSeq Size 8034
RefSeq ORF 3507
Synonyms Ankhzn; mKIAA1255; ZFYVE14
Summary Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport (By similarity). Involved in macropinocytosis; the function is dependent on Rab5-GTP.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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