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Taok3 (NM_001081308) Mouse Recombinant Protein

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SKU
TP524145
Purified recombinant protein of Mouse TAO kinase 3 (Taok3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR224145 representing NM_001081308
Red=Cloning site Green=Tags(s)

MRKGALKDPEIADLFFKDDPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAVKKMSYSGKQTHEKWQDIL
KEVKFLQQLKHPNTIEYKGCYLKEHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHF
HSLIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGIT
CIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREWTDSFRRFVDYCLHKIPQERPAAVELLRHDFIRRE
RPPKVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEEEEDGEQGSNLNREVDSLGSIHSI
PSTSVSTGSRSSSVNSMQEVMDESSSELVMMQEDEGTANSSASTVHKKDHVFVRDEAGHGDPRPEPRPTQ
SVQSRALHYRNRERFATIKSASLVTRQIHEHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHR
LKLQKEVETHANNSSIELEKLAKKQVATIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICK
EKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDRNCRFFKRKIMIKRHEVEQQN
IREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRK
HVMELRQQPKNLKAMEMQIKKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKAILKTLKDEQTRKLAILAE
QYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQRVSLRRA
HLEQKIEEELAALQKERSERIKTLLERQERETETFDMESLRMGFGNLVTLDFPKEDYR

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 105.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001074777
Locus ID 330177
UniProt ID Q8BYC6
Cytogenetics 5 F
RefSeq Size 4258
RefSeq ORF 2694
Synonyms 2900006A08Rik; A130052D22; A430105I05Rik
Summary Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF) (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Enzyme: Kinases, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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