Uba1 (NM_001136085) Mouse Recombinant Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 117.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001129557 |
| Locus ID | 22201 |
| UniProt ID | Q02053 |
| Cytogenetics | X 16.15 cM |
| RefSeq Size | 4073 |
| RefSeq ORF | 3174 |
| Synonyms | A1; A1S9; Sb; Sbx; Ube-1; Ube1x |
| Summary | This gene encodes a member of the ubiquitin-activating E1 family. The encoded protein initiates the ubiquitin activation and transfer cascade, catalyzing the first step in ubiquitin conjugation to mark cellular proteins for proteasome degradation. Ubiquitin activating enzymes use ATP to form a thioester between a conserved catalytic cysteine of the enzyme and the C-terminal carboxylate of ubiquitin. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2013 |
| Protein Categories | Enzyme: Ligase, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases |
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