Rab3gap1 (NM_178690) Mouse Recombinant Protein

CAT#: TP511377

Purified recombinant protein of Mouse RAB3 GTPase activating protein subunit 1 (Rab3gap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >MR211377 representing NM_178690
  Red=Cloning site Green=Tags(s)
  
  MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGPSLGKPLEKGIFTSGTWEERSDEISFADF
  RFSVTHHYLVQESPDKERKDEELEDAIPQSMQDLLCMNNDFPPRAHCLVRWYGLREFVVIAPAAHSDAVL
  SESKCNLLLSSISIALGNTGCQVPLFVQIHHKWRRMYMGECQGPGVRTDFEMVHLRKVPSQYTHLSGLLD
  IFKSKIGCPLTPLPPVSIAIRLTYVLQDWQQYFWPQQPPDIDALVGGEVGGLEFGKLPFGACEDPISELH
  LATTWPHLTEGIIVDNDVYSDLDPVQAPHWSVRVRKADNPQCLLGDFVTEFLKICRRKESTDEILGRSTF
  EEEGREVADITHALSKLTEPAPVPIHKLSVSNMVHTAKKKIRKHRGEESPLNSDVLNTILLFLFPDAVSE
  KPLDGTTSIDNSIPAPEAGDYTLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFR
  WENNFLIPGLASGSPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSLSDSTTSAYPGDAGKTGGQLGLDH
  LRDTEKEKGEVGKSWDSWSDSEEEFFECLSDTEDLKGNGQESGKKGGPKEMANLKPEGRLHQHGKLTLLH
  NGEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCFLEDFVR
  WYSPRDYIEEEVTDEKGNVVLKGELSARMKIPSNMWVEAWETAKPVPARRQRRLFDDTREAEKVLHYLAM
  QKPADLARHLLPCVIHAAVLKVKEEESLENIPSVKKIIKQIIAHSSKVLHFPNPEDKKLEEIILQITTVE
  AIIARARSLKAKFGTEKCEHEEEKEGLERFVSCLLEQPEVSVTGAGRGHAGRIIHKLFVNAQRAAAVALP
  EEELKKSGCPEERRQTLVSDFPPPAGRELILRATVPRPAPYSKALPQRMYSVLTKEDFRLAGAFSSDTSF
  F
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-MYC/DDK
• Predicted MW: 110.6 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_848805
• Locus ID: 226407
• UniProt ID: Q80UJ7
• Cytogenetics: 1 E3
• Refseq Size: 4251
• Refseq ORF: 2943
• Synonyms: 1700003B17Rik; 4732493F09Rik; AL117896; p130; Rab3gap
• Summary: Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters (By similarity).[UniProtKB/Swiss-Prot Function]