Smarcad1 (BC042442) Mouse Recombinant Protein

SKU
TP510897
Purified recombinant protein of Mouse SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1`, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
  $1,020.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR210897 representing BC042442
Red=Cloning site Green=Tags(s)

MDGAIAAALLMFGDAGGGPRKRKLSSSSEEDDVNDDQSVKQPRGDRGEESNESAEASSNWEKQESIVLKL
QKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDVQCASQSEVTNGKEVARNQNYSKNATKIKMKQ
KISVKPQNGFNKKRKKNVFNPKKAVEDSEYDSGSDAGSSLDEDYSSCEEVMEDGYKGKILHFLQVSSIAE
LTLIPKCSQKKAQKITELRPFNNWEALFTKMSKINGLSEDLIWNCKTVIQERDVVIRLMNKCEDISNKLT
KQVTMLTGNGGGWNREQPSLLNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLF
QEGNKGPHLIVVPASTIDNWLREVNLWCPSLNVLCYYGSQEERKQIRFNIHNKYEDYNVIVTTYNCAISS
SDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINARNRLLLTGTPVQNNLLELMSLLNFVMPHMFS
SSTSEIRRMFSSKTKPADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKLLPPKKDRIELCAMSEKQEQL
YSGLFNRLKKSINNLEKNTEMCNVMMQLRKMANHPLLHRQYYTPEKLKEMSQLMLKEPTHCEANPDLIFE
DMEVMTDFELHVLCKQYQHINSYQLDMDLILDSGKFRALGCILSELKQKGDRVVLFSQFTMMLDILEVLL
KHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAE
DRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEADEGSMPADIATLLKTSMGL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 153.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
Locus ID 13990
UniProt ID Q04692
Cytogenetics 6 30.11 cM
RefSeq Size 4193
RefSeq ORF 2508
Synonyms AV081750; AW226546; D6Pas1; Etl1; mKIAA1122
Summary DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication. Acts at replication sites to facilitate the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restoration of silencing (By similarity).UniProtKB/Swiss-Prot Function
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