Gars (NM_180678) Mouse Recombinant Protein

SKU
TP510334
Purified recombinant protein of Mouse glycyl-tRNA synthetase (Gars), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
  $1,020.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR210334 protein sequence
Red=Cloning site Green=Tags(s)

MPCLLPSLLRATRAALPLLSPPRVVAASASQRLLSAPAQPAASRSSMDSAEELLAPLRLAVRQQGDFVRK
LKEDKAPQVDVDRAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDF
GPVGCALKNNIIQAWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKA
HLQKLMSDKKCSAEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPTTGNDLSPPVPFNLMFQTFIGPGG
NMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPTEK
DHPKFQSVADLCLYLYSAKAQVTGQSARKMRLGDAVEQGVINNSVLGYFIGRIYLYLTKVGISPDKLRFR
QHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPN
KGAVGKAYKKDAKLVLEYLSACDECYISEMELLLSEKGEFTIETEGKTFQLTKDMVSVKRFQKTLHVEEV
VPSVIEPSFGLGRIMYTILEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTR
NGVSHKVDDSSGSIGRRYARTDEIGVAFGITIDFDTVNKTPHTATLRDRDSMRQIRAEVSELPSVVRDLA
NGNITWADVEARYPLFEGQETGKKETVEE

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 81.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_851009
Locus ID 353172
UniProt ID Q9CZD3
Cytogenetics 6 27.29 cM
RefSeq Size 2390
RefSeq ORF 2187
Synonyms Gena201; GENA202; Nmf249; Sgrp23
Summary Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.UniProtKB/Swiss-Prot Function
Protein Categories Enzyme: Ligase, Intracellular Proteins, Nervous system: Neurodegenerative diseases
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Documents
Resources

file-alt Citations

Glycyl-tRNA synthetase induces psoriasis-like skin by facilitating skin inflammation and vascular endothelial cell angiogenesis
Zheng, Chen, Xu et al
J Invest Dermatol (2023)
Cited by 9
AI Summary: OriGene’s recombinant mouse GARS protein (Cat# TP510334) was used for intradermal injection in mice to investigate the role of GARS in inducing psoriasis-like skin inflammation and angiogenesis in this study.
Snippet: For the rmGARS group, recombinant mouse gars protein (Cal#. TP510334, OriGene, USA, 500 ng once per ear, diluted in 25 μl) was intradermally injected into the left ear of mice every other day for 30 consecutive days (15 times in total)
Showing 1-1 of 1 papers.
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