Nln (NM_029447) Mouse Recombinant Protein

SKU
TP510154
Purified recombinant protein of Mouse neurolysin (metallopeptidase M3 family) (Nln), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
  $1,020.00
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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR210154 protein sequence
Red=Cloning site Green=Tags(s)

MITLCLSALRGLHRAGGSRIRLRMTLGREAASPLQAMSSYTAAGRNVLRWDLSPEQIRTRTEELIAQTKQ
VYDTVGTINLEDVTYENCLQVLADIEVKYIVERTMLDFPQHVSSDREVRAASTEADKRLSRFDIEMSMRE
DVFQRIVHLQETCDLEKIKPEARRYLEKSIKMGKRNGLHLPEHVKNEIKSMKKRMSELCIDFNKNLNEDD
TSLVFSKAELGALPDDFIDSLEKTDEDKYKVTLKYPHYFPVMKKCCVPETRRKMEMAFHTRCKEENTIIL
QQLLPLRAQVAKLLGYNTHADFVLELNTAKSTSHVATFLDDLSQKLKPLGEAEREFILSLKKKECEERGF
AYDGKINAWDLHYYMTQTEELKYSVDQESLKEYFPIEVVTEGLLSIYQELLGLSFEQVADAHVWNKSVSL
YTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMSVAALVVNFSQPIAGRPSLLRHD
EVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDIDSLRKLSKHYRDGHPITDELL
EKLVASRLVNTGLLTLRQIVLSKVDQSLHTNASLDAASEYAKYCTEILGVAATPGTNMPATFGHLAGGYD
GQYYGYLWSEVFSMDMFHSCFRKEGIMNPEVGMKYRNLILKPGGSLDGMDMLQNFLQREPNQKAFLMSRG
LNAS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 80.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_083723
Locus ID 75805
UniProt ID Q91YP2
Cytogenetics 13 D1
RefSeq Size 3780
RefSeq ORF 2112
Synonyms 4930472G13Rik; C79345
Summary Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A.UniProtKB/Swiss-Prot Function
Protein Categories Enzyme: Peptidases, Intracellular Proteins
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Documents
Resources

file-alt Citations

Discovery of a pyridine-piperazine-based small molecule that enhances the activity of peptidase neurolysin
ElSayed ElZorkany, Kandil, Jayaraman et al
J Pharmacol Exp Ther (2026) 393 (3), 103827 DOI: 10.1016/j.jpet.2026.103827
Cited by 1
AI Summary: OriGene contributed to this study by providing the mouse Nln protein (product # TP510154), which was used to assess the effects of the discovered small molecule on neurolysin activity.
Snippet: Mouse Nln was purchased from OriGene (product # TP510154). Human angiotensin converting enzyme (ACE;product # 929-ZN), ACE2 (product # 933-ZN), and neprilysin (NEP;product # 1182-ZNC) were obtained from R&D Systems
Showing 1-1 of 1 papers.
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