Sema7a (NM_011352) Mouse Recombinant Protein

CAT#: TP509876

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Purified recombinant protein of Mouse sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (Sema7a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug



USD 748.00


Availability*
6 Weeks

Size
    • 20 ug


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Specifications

Product Data
Description Purified recombinant protein of Mouse sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (Sema7a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Species Mouse
Expression Host HEK293T
Expression cDNA Clone or AA Sequence A DNA sequence from Mouse cDNA ORF Clone, MR209876, encoding Mouse full-length Sema7a.
Tag C-MYC/DDK
Predicted MW 75.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_035482
Locus ID 20361
UniProt ID Q9QUR8
Cytogenetics 9 B
Refseq Size 3290
Refseq ORF 1992
Synonyms 2900057C09Rik; CDw108; H-Sema-L; H-Sema K1; M-Sema-L; sema K1; Semal; sema L
Summary Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.[UniProtKB/Swiss-Prot Function]

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