Wrnip1 (NM_030215) Mouse Recombinant Protein

SKU
TP509831
Purified recombinant protein of Mouse Werner helicase interacting protein 1 (Wrnip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
  $1,020.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR209831 representing NM_030215
Red=Cloning site Green=Tags(s)

MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAK
RRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPARKGMG
KRPAAAAAAGSASPRSWDEAEAQEEEEAGVDGDGDADVDGEDDPGHWDADAADASFGVSAGRAHPRALAA
EEIRQMLEGKPLADKMRPDTLQDYIGQSRAVGQETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANNS
KKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGA
TTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNCSSEPSVFIE
DKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKVFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRA
GEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGC
HFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPPVPLHLRNAPTRLMKDLGYGKGY
KYNPMYSEPVDQDYLPEELRGVDFFKQRRC

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 72.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_084491
Locus ID 78903
UniProt ID Q91XU0
Cytogenetics 13 A3.2
RefSeq Size 2642
RefSeq ORF 1980
Synonyms 4833444L21Rik; WHIP; Wrnip
Summary Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG-I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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