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Lrwd1 (NM_027891) Mouse Recombinant Protein

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SKU
TP509749
Purified recombinant protein of Mouse leucine-rich repeats and WD repeat domain containing 1 (Lrwd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR209749 protein sequence
Red=Cloning site Green=Tags(s)

MAPLTPQLLLQRGRPKTDKLGKIQSLNLSGLQLLSEHLDPNLLGRLKKLRELDLSNNLLETLPANLGLSH
LRILRCTNNQLGDVTALHQFPELEELNLEGNPFLTVSDNLKVSFLLPKLRKVNGKDTASTCSQVENLDRE
LMDRVTAHWQKFIATVSPEEETDKVRADFMRSAVRDVCYGPESLIEFTQWRVRMIAEELVASGGAQVQDA
KVPVEHPQAAGASKFRAREVASKRPGKDPVTLPPSKRVRALPPAQAEGSPMGADGGQAALHLEPLHFLQC
HSRNNSPKDLETQLWACAFEPAREEGHSRATSQTVATCGGEAVCVIDCQTGLVLHKYKVPGEEFFSVAWT
ALTVVTQAGHKKRWNMLAAAGLRGMVRLLHVRAGFCCSVIRAHKKAIATLCFSPSHETHLFTASYDKRII
LWDIGVPNQDYKFQASQLLTLNCGSVPLRLCPVATCPDDFLLAGCEGGCYCWDVRLDQPQKQRVCEVNFI
FSEDSKVSGQRVDGLAFVNEDVVASKGSGQGTIYLWSWSQTWAGRGRQSVLPVVILVRLQWSPTNLAYFS
LSTCPGKNLVLCGDEEGSVWIYDVEHLLKEPPQATTLQPPTQILKWPQPTALGQPVTKTMINTVVANAAF
TYLTALTDSNIVSIWRRC

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 71.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_082167
Locus ID 71735
UniProt ID Q8BUI3
Cytogenetics 5 G2
RefSeq Size 2201
RefSeq ORF 1944
Synonyms 1200011O22Rik; AU042569; AW548074; Orca
Summary Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation (By similarity). Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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