Otud5 (NM_138604) Mouse Recombinant Protein

CAT#: TP508940

Purified recombinant protein of Mouse OTU domain containing 5 (Otud5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >MR208940 representing NM_138604
  Red=Cloning site Green=Tags(s)
  
  MTILPKKKPPPPDADPANEPPPPGPLPPAPRRGAGVGVGGGGTGVGGGERDRDSGVVGARPRASPPPQGP
  LPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGATTAGVGAAGVVVGVGGTVGVG
  GCCSGPGHSKRRRQAPGVGAVGGASPEREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDK
  KGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHG
  NHIEMQAMAEMYNRPVEVYQYSTEPINTFHGIHQNEDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPSF
  KPGFAEQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQVRGPS
  QPRKASATCSSATAAASSGLEEWTSRSPRQRSSASSPEHPELHAELGIKPPSPGTVLALAKPPSPCAPGT
  SSQFSAGGDRATSPLVSLYPALECRALIQQMSPSAFGLNDWDDDEILASVLAVSQQEYLDSMKKNKVHRE
  PPPDKS
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-MYC/DDK
• Predicted MW: 60.8 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_613070
• Locus ID: 54644
• UniProt ID: Q3U2S4
• Cytogenetics: X 3.54 cM
• Refseq Size: 2505
• Refseq ORF: 1698
• Synonyms: AA407879; AI553596; BB114028; DUBA; DXImx46e; Sfc7
• Summary: Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function]