Tgfbr1 (NM_009370) Mouse Recombinant Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 56.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_033396 |
| Locus ID | 21812 |
| UniProt ID | Q64729 |
| Cytogenetics | 4 26.02 cM |
| RefSeq Size | 5735 |
| RefSeq ORF | 1509 |
| Synonyms | AL; Alk; Alk-5; ALK5; AU017191; ESK2; Tbet; Tbeta; TbetaR-I; TbetaRI; TGFR-1 |
| Summary | This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2015 |
| Protein Categories | Cancer: Gastrointestinal, Cardiovascular diseases, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins |
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