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Arhgap22 (BC038272) Mouse Recombinant Protein

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SKU
TP508068
Purified recombinant protein of Mouse Rho GTPase activating protein 22 (cDNA clone MGC:47316 IMAGE:4237331), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR208068 protein sequence
Red=Cloning site Green=Tags(s)

MASSQRDMEDWVQAIRRVIWAPLGRGIFGQRLEDTVHHERKFGPRLAPLLVEQCVDFIRERGLSEEGLFR
MPGQANLVRDLQDSFDCGEKPLFDRFLDEVQAHSDVNKMSVQNLATVFGPNILRPQIEDPVTIMEGTSLV
QHLMTVLIRKHGQLFAATSLEEPASPHGTVEWGSEEVTRDHRGEPGSPGLPTHRTSSLDGPAAAVLSRTS
PPRLGSQTGPAATSPGKKMHTLPVWKSSFRQQGSRSESPKGVNSSLEVPIISSGGNWLINGLSSLRSHRR
ASSGDRLKDTGSAQRLSTYDNVPPSSQFSSTASVASTSWSVASSSREASVSSCTACRASNSSACSSLHTE
WALEPSPLPSSSEGHQSPDLGHSLDEPCVGSGSSEPNDPGSPTQAHVRRCRALQGQVAELRAELCQQRTE
YKRSLKSIEEGSADLRKQMSRLEEELDQERKKYAMLEIKLRNSERAREDAERRNQLLQREMEEFFSTLGS
LTTGTKGSRAPE

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 55.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
Locus ID 239027
UniProt ID Q8BL80
Cytogenetics 14 B
RefSeq Size 2108
RefSeq ORF 1506
Synonyms MGC47316, RHOGAP2
Summary Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter.UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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