Wdr34 (NM_001008498) Mouse Recombinant Protein

SKU
TP506644
Purified recombinant protein of Mouse WD repeat domain 34 (Wdr34), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
  $1,020.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR206644 protein sequence
Red=Cloning site Green=Tags(s)

MVIRELNNNWQSHAFDGYEVNWTEQQQTVSCLHTLVYPLAQGQGLHVTGISWNSTGSVLACAYGRLDDGD
WSTLKSYVCTWNLDRQGLNPQQPSVVVEVPSAVMCLAFHPTQPSHIAGGLYSGEVLVWDMSRPEDPLLWR
TGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGKVLLWRGSGAGQLRLTKGFALAVQQLPRSTKLKK
PPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLASEVAALTRMPSSVPLRAPVQFTFSPHGGPVYS
VSCSPFHRNLFLSAGTDGHVHLYSMLQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQK
SSQKPTVSITQTQDGSPVYCLEFNSQQTQLLAAGDAKGMVKVWQLSTAFTEQGPREVEDLDQLEAEITT

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 46 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001008498
Locus ID 71820
UniProt ID Q5U4F6
Cytogenetics 2 B
RefSeq Size 1812
RefSeq ORF 1257
Synonyms 3200002I06Rik
Summary Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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