Zfp830 (NM_025884) Mouse Recombinant Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 40.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_080160 |
| Locus ID | 66983 |
| UniProt ID | Q8R1N0 |
| Cytogenetics | 11 C |
| RefSeq Size | 3278 |
| RefSeq ORF | 1089 |
| Synonyms | 2410003C20Rik; AV301118; AW048207; Ccdc16; Omcg1; Znf830 |
| Summary | May play a role in pre-mRNA splicing as component of the spliceosome (By similarity). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity (PubMed:21191184, PubMed:23213458, PubMed:25168238, PubMed:15988037). During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation (PubMed:21191184). Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells (PubMed:23213458). During the embryo preimplantation, controls different aspects of M phase (PubMed:15988037). During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (PubMed:25168238).UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
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