Rab32 (NM_026405) Mouse Recombinant Protein
SKU
TP502577
Purified recombinant protein of Mouse RAB32, member RAS oncogene family (Rab32), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
$1,020.00
4 Weeks*
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 25.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_080681 |
| Locus ID | 67844 |
| UniProt ID | Q9CZE3 |
| Cytogenetics | 10 A1 |
| RefSeq Size | 2054 |
| RefSeq ORF | 669 |
| Synonyms | 2810011A17Rik; AU022057 |
| Summary | Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium (By similarity). Plays an important role in the control of melanin production and melanosome biogenesis (By similarity). In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (PubMed:26620560).UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Burkholderia pseudomallei BopE suppresses the Rab32-dependent defense pathway to promote its intracellular replication and virulence
Rao, Zhang, Qiao et al
mSphere (2024)
Rao, Zhang, Qiao et al
mSphere (2024)
Cited by 1
AI Summary: OriGene products Rab32 (TP502577) and Rac1 (TP527648) recombinant proteins were used in nucleotide exchange assays to investigate the interaction between BopE and host Rab32, elucidating the mechanism by which BopE suppresses Rab32-dependent defense pathways during Burkholderia pseudomallei infection.
Snippet: Nucleotide exchange assays were conducted using fluorescent N-methylanthraniloyl-GDP (Mant-GDP, Molecular Probes), following a modified method from a previous report (33). Briefly, Rab32 (Origene, TP502577) or Rac1 (Origene, TP527648) equilibrated in loading buffer (20 mmol/L HEPES-NaOH [pH 7.5], 50 mmol/L NaCl, 0.5 mmol/L MgCl2, 5 mmol/L EDTA, 1 mmol/L DTT) was loaded with 20-fold excess
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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