Pf4 (NM_019932) Mouse Recombinant Protein

SKU
TP500359
Purified recombinant protein of Mouse platelet factor 4 (Pf4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
  $1,020.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR200359 representing NM_019932
Red=Cloning site Green=Tags(s)

MSVAAVFRGLRPSPELLLLGLLFLPAVVAVTSAGPEESDGDLSCVCVKTISSGIHLKHITSLEVIKAGRH
CAVPQLIATLKNGRKICLDRQAPLYKKVIEKILES

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 11.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_064316
Locus ID 56744
UniProt ID Q9Z126
Cytogenetics 5 E1
RefSeq Size 525
RefSeq ORF 315
Synonyms Cxcl4; Scyb4
Summary Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Chemokines, Cytokines, Secreated Proteins
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Documents
Resources
Other "Pf4" proteins (1)
SKU Description Size Price
TP723860 Purified recombinant protein of Mouse platelet factor 4 (Pf4 / PF-4) 10 ug
$345.00

file-alt Citations

Critical role of CXCL4 in the lung pathogenesis of influenza (H1N1) respiratory infection
Guo, Feng, Wang et al
Mucosal Immunol (2017)
AI Summary: OriGene’s recombinant CXCL4 protein was used to treat CXCL4-deficient mice, enabling the researchers to specifically assess the role of CXCL4 in influenza-induced lung pathology.
Snippet: To demonstrate CXCL4-specific effects in the CXCL4 −/− mice, H1N1-infected CXCL4 −/− mice were given recombinant CXCL4 (5 μg per mouse) (OriGene, Beijing, China) on day 0 and daily postinfection by intravenous injection via the retro-orbital plexus as described ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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