CITED2 (NM_001168388) Human Recombinant Protein
SKU
TP329801M
Purified recombinant protein of Homo sapiens Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2), transcript variant 2, 100 µg
$2,950.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 28.9 |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | NULL or Add: Recombinant proteins was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001161860 |
| Locus ID | 10370 |
| UniProt ID | Q99967 |
| Cytogenetics | 6q24.1 |
| RefSeq ORF | 810 |
| Synonyms | ASD8; MRG-1; MRG1; P35SRJ; VSD2 |
| Summary | The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, May 2012 |
| Protein Categories | Cardiovascular diseases, Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway
Shin, Lee, Lee et al
Nat Commun (2018) 9 (1), 4113 DOI: 10.1038/s41467-018-06606-2
Shin, Lee, Lee et al
Nat Commun (2018) 9 (1), 4113 DOI: 10.1038/s41467-018-06606-2
AI Summary: OriGene contributed to this study by providing human recombinant proteins of CITED2, PRMT5, P300, and NCL, which were used to investigate the molecular mechanisms underlying prostate cancer metastasis.
Snippet: anti-p-AKT, anti-AKT and anti-E-cadherin from Cell Signaling (Danvers, MA);anti-FLAG, anti-MYC, and anti-HA from Sigma-Aldrich (St. Louis, MO);and anti-ERG and anti-α-SMA from Abcam (Cambridge, MA). MK2206 was purchased from Selleckchem. Human recombinant proteins of CITED2, PRMT5, P300, and NCL were purchased from Origene
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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