CD105 (ENG) (NM_001114753) Human Recombinant Protein

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SKU
TP326069
Purified recombinant protein of Homo sapiens endoglin (ENG), transcript variant 1, 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC226069 representing NM_001114753
Red=Cloning site Green=Tags(s)

MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERDEVTYTTSQVSKGCVAQAPNAILEVHVLFLE
FPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAYNSSLVTFQEPPGVNTTELPS
FPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLSFCMLEASQDMGRTLEWRPRTPALVRGCHLE
GVAGHKEAHILRVLPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFK
IFPEKNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTC
SPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM
ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVSPSVSEFLLQL
DSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVPIPKTGTLSCTVALRPKTGSQ
DQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRSPSKREPVVAVA
APASSESSSTNHSIGSTQSTPCSTSSMA

SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 68 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001108225
Locus ID 2022
UniProt ID P17813
Cytogenetics 9q34.11
RefSeq ORF 1974
Synonyms END; HHT1; ORW1
Summary This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2013
Protein Categories CD Markers, Growth Factors, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
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Other "CD105" proteins (8)
SKU Description Size Price
PH321699 ENG MS Standard C13 and N15-labeled recombinant protein (NP_000109) 10 ug
$3,360.00
PH326069 ENG MS Standard C13 and N15-labeled recombinant protein (NP_001108225) 10 ug
$3,360.00
LC424919 Lyophilized ENG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426509 Lyophilized ENG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424919 Transient overexpression lysate of endoglin (ENG), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY426509 Transient overexpression lysate of endoglin (ENG), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP321699 Recombinant protein of human endoglin (ENG), transcript variant 2, 20 µg 20 ug
$737.00
TP721000 Purified recombinant protein of Human endoglin (ENG), transcript variant 2 10 ug
$275.00

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