PACRG (NM_001080378) Human Recombinant Protein
$867.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 29.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | In vitro ubiquitination assay (PMID: 28038320) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001073847 |
| Locus ID | 135138 |
| UniProt ID | Q96M98 |
| Cytogenetics | 6q26 |
| RefSeq Size | 1585 |
| RefSeq ORF | 771 |
| Synonyms | GLUP; HAK005771; PACRG2.1; PARK2CRG |
| Summary | This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PACRG" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH322240 | PACRG MS Standard C13 and N15-labeled recombinant protein (NP_001073847) | 10 ug |
$3,360.00
|
|
| LC407578 | Lyophilized PACRG HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC421606 | Lyophilized PACRG HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC421607 | Lyophilized PACRG HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY407578 | Transient overexpression lysate of PARK2 co-regulated (PACRG), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY421606 | Transient overexpression lysate of PARK2 co-regulated (PACRG), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY421607 | Transient overexpression lysate of PARK2 co-regulated (PACRG), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis
Gong, Schumacher, Wu et al
Neoplasia (2016) 19 (2), 75-83 DOI: 10.1016/j.neo.2016.12.006
Gong, Schumacher, Wu et al
Neoplasia (2016) 19 (2), 75-83 DOI: 10.1016/j.neo.2016.12.006
AI Summary: OriGene’s recombinant human BCL-XL protein was used in this study to investigate the interaction between PARK2 and BCL-XL in the regulation of apoptosis.
Snippet: Recombinant proteins of human BCL-XL and PARK2 were purchased from Origene Technologies Inc. and Boston Biochem, respectively
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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