Osteocalcin (BGLAP) (NM_199173) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 8.7 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_954642 |
| Locus ID | 632 |
| UniProt ID | P02818 |
| Cytogenetics | 1q22 |
| RefSeq Size | 498 |
| RefSeq ORF | 300 |
| Synonyms | BGP; OC; OCN |
| Summary | This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. provided by RefSeq, Jun 2015 |
| Protein Categories | Growth Factors, Secreated Proteins |
| Protein Families | ES Cell Differentiation/IPS, Secreted Protein |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Osteocalcin" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH320555 | BGLAP MS Standard C13 and N15-labeled recombinant protein (NP_954642) | 10 ug |
$3,360.00
|
|
| LC404673 | Lyophilized BGLAP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY404673 | Transient overexpression lysate of bone gamma-carboxyglutamate (gla) protein (BGLAP) (as WB positive control) | 100 ug |
$436.00
|
|
| TP701039 | Purified recombinant protein of Human bone gamma-carboxyglutamate (gla) protein (BGLAP), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug | 50 ug |
$900.00
|
|
Citations
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