alpha Defensin 1 (DEFA1) (NM_004084) Human Recombinant Protein

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SKU
TP318421
Recombinant protein of human defensin, alpha 1 (DEFA1), 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC218421 representing NM_004084
Red=Cloning site Green=Tags(s)

MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMDCYCRI
PACIAGERRYGTCIYQGRLWAFCC

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 10 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_004075
Locus ID 1667
UniProt ID P59665
Cytogenetics 8p23.1
RefSeq Size 490
RefSeq ORF 282
Synonyms DEF1; DEFA2; HNP-1; HP-1; HP1; MRS
Summary Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. provided by RefSeq, Oct 2014
Protein Categories Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
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Other "alpha Defensin 1" proteins (3)
SKU Description Size Price
PH318421 DEFA1 MS Standard C13 and N15-labeled recombinant protein (NP_004075) 10 ug
$3,360.00
LC418227 Lyophilized DEFA1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418227 Transient overexpression lysate of defensin, alpha 1 (DEFA1) (as WB positive control) 100 ug
$436.00

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