USP2 (NM_171997) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 45.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_741994 |
| Locus ID | 9099 |
| UniProt ID | O75604 |
| Cytogenetics | 11q23.3 |
| RefSeq Size | 1378 |
| RefSeq ORF | 1188 |
| Synonyms | UBP41; USP9 |
| Summary | This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Aug 2011 |
| Protein Categories | Enzyme: Peptidases, Intracellular Proteins |
| Protein Families | Protease |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "USP2" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH317695 | USP2 MS Standard C13 and N15-labeled recombinant protein (NP_741994) | 10 ug |
$3,360.00
|
|
| LC401351 | Lyophilized USP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC403527 | Lyophilized USP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401351 | Transient overexpression lysate of ubiquitin specific peptidase 2 (USP2), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY403527 | Transient overexpression lysate of ubiquitin specific peptidase 2 (USP2), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
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