IL17RD (NM_017563) Human Recombinant Protein
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 82.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Co-immunoprecipitation (PMID: 25808990) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_060033 |
| Locus ID | 54756 |
| UniProt ID | Q8NFM7 |
| Cytogenetics | 3p14.3 |
| RefSeq Size | 8736 |
| RefSeq ORF | 2217 |
| Synonyms | HH18; IL-17RD; IL17RLM; SEF |
| Summary | This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jan 2016 |
| Protein Categories | Cytokines, Endocrine and metabolic diseases, Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "IL17RD" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH317198 | IL17RD MS Standard C13 and N15-labeled recombinant protein (NP_060033) | 10 ug |
$3,360.00
|
|
| LC413705 | Lyophilized IL17RD HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413705 | Transient overexpression lysate of interleukin 17 receptor D (IL17RD) (as WB positive control) | 100 ug |
$665.00
|
|
Citations
Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions
Mellett, Atzei, Bergin et al
Nat Commun (2015) 6, 6669 DOI: 10.1038/ncomms7669
Mellett, Atzei, Bergin et al
Nat Commun (2015) 6, 6669 DOI: 10.1038/ncomms7669
Cited by 43
AI Summary: OriGene’s recombinant human IL-17RD protein was used in this study to investigate the regulatory role of IL-17RD in Toll-like receptor signalling.
Snippet: anti-TLR4 (1:500), anti-ubiquitin (1:500) and anti-p65 (1:500) antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA). Recombinant human MyD88 was from Novus Biologicals (Littleton, CO) and recombinant human IL-17RD was from Origene (Rockville, MD)
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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